He would go without breathing for multiple seconds. Since starting my new supplement regimen of Omega-3 (new), Vitamin D (new) and my usual multi-vitamin, my whole being seems to have been transported back in time and I just feel better, stronger, faster both physically and mentally. Any time I do lunges and squats and heavy leg days Im a zombie for two days. As a result, the web page can not be displayed. Rogan: Do you use anything to help you sleep in terms of a meditation app or do you . They talked about the benefits of saunas on your sleep, blue light glasses, sleep apnea, and more. So were laying in bed watching a show and Im totally relaxed in bed. Dr. Rhonda Patrick obtained her Ph.D. in biomedical science from the University of Tennessee Health Science Center in Memphis, Tennessee. So theyre like melatonin is not being produced so if we travel to the in-laws and they have lights on Im going around and turning them off because I want my son to go to bed at a normal hour. I was on a plane once and this guy behind me and he was kind of a heavy fellow and he was really snoring loud. rperciav 9 yr. ago we need to fix this, Even a degree in nutrition has flaws as a lot of the dogma has changed and they are not often very hardcore science in their focus, Rhonda keeps switching her fields from chemistry, aging, cancer, nutrition and the brain, This helps you have new perspectives that people who only do one thing dont see, Consumer focused blood tests on all blood markers (e.g. Pixel Eyewear Designer Computer Glasses These glasses are specifically designed to reduce eye strain, dry eyes, and headaches associated with viewing computer screens and cell phones late into the night. This is an unofficial transcript meant for reference. Much of the scientific studies detailing the benefits involve the dry sauna, The real benefits come when you get to 180 degrees, Frequent sauna use increases mitochondrial biogenesis and allows for improvements in mitochondrial function, Using the sauna before a workout has been shown to reduce DOMS (delayed onset muscle soreness) they dont specify for how long to use the sauna pre workout, Hyperthermia (and exercise) activates IL-6(its an inflammatory cytokine) like crazy, The greater the production of IL-6, the greater the reduction in depressive symptoms, This is the same thing released from muscle tissue after exercise, In response to this, the body has an anti-inflammatory effect, Giving people NSAIDS (nonsteroidal anti-inflammatory agents) prior to a workout, blunts IL-6 production, and many of the benefits of exercise are negated (like improved insulin sensitivity), There are studies that show hot yoga improves depressive symptoms, Its is responsible for what one might call, a dizziness feeling, at the tail end of a sauna session that feeling of oh god, I have to get out, Dynorphin binds to kapa opioid receptors in the brain, This causes a feedback response in other opioid receptors in the brain (mu opioid receptors) which bind to beta endorphins, Joe has one in his studio, he tries to do it 2-3 times a week, Hell often do it in the morning, sometimes for 2 hours, Joe gets his blood checked every 6 months, 300 grams of brussel sprouts a day increased blood glutathione plasma levels by 1.4 fold. In this this episode of The Matt Walker Podcast, Matt Walker & Craig Canapari continue their two part discussion behind the science of FREE when you join over 50,000 subscribers to the Podcast Notes newsletter. "People are dying from heart attacks and blood clots, and even myocarditis, 100-fold times more than the vaccines.". I started reading about this stuff and a lot of the treatments are stuff like benzos and hell no Im not going to take benzos. Ive had multiple incidents where back when I was nursing my son where he was on a nursing pillow when Im very relaxed producing oxytocin and it tells me Im in REM sleep. YzM0MDI1NTI5NzcwOWI5OTNlOTAzYTdiNzMyYzI3YzBhYmJhZGEwOTU1MjAy With a PhD in biomedical science and a Bachelor's of Science degree in biochemistry/chemistry she is an expert and vocal spokesperson for health research. You can do it but its difficult, and most people probably wont do it, Theres all these other things present in plants that people following a carnivore diet are missing out on , Broccolli sprouts are the biggest source, but its also present in brussel sprouts, Sulforaphane has been found to improve symptoms of autism, There are literally so many beneficial things that come from eating vegetables too many to mention, Why? doesn't how usually worship at her altar and spread the good word of Dr. Rhonda Patrick? Dr. Rhonda Patrick on Vaccine Misinformation and Long-haul Covid - YouTube 0:00 / 14:54 Get the latest information from the CDC. Itll tell you: hey, you should get to bed since youve been getting up at 6 oclock in the morning so you should go to bed by 10 tonight. Rogan: The idea is that a lot of people have problems with CPAPs. Rogan: A lot of football players get it because your neck, the muscles are really big. 160 kvothes-lute 1 yr. ago right? She is also the host of Found My Fitness podcast. The Joe Rogan Experience #502 - Dr. Rhonda Patrick 2014-05-16 | Dr. Rhonda Patrick is a Ph.D in biomedical science and expert on nutritional health. . Podcast Notes isnot associated or affiliated with the source podcast (unless otherwise stated). Rogan: Like crazy.if(typeof ez_ad_units != 'undefined'){ez_ad_units.push([[300,600],'sleepline_com-leader-4','ezslot_13',666,'0','0'])};__ez_fad_position('div-gpt-ad-sleepline_com-leader-4-0'); Patrick: But when you wear it you dont snore? Couldn't find this anywhere online so here's what I've found. Its amazing. You hold your breath for long periods of time. Rogan: If youre looking at your screens do you use blue-light blocking glasses? First, the EAR (estimated average intake) is looked at you look at a given population, and determine how much of a given micronutrient the population needs so that 50% of the population has adequate levels, The RDA is set from that, 2 standard deviations above, Scurvy happens when you dont have enough vitamin C for collagen production (this is thought to be about only 10mg/day it doesnt take much), Vitamin C has two forms ascorbic acid (the reduced form aka the antioxidant) and an oxidized form (dehydroascorbic acid), The RDA for vitamin C is 90 mg/day for men and 75 mg/day for women, Its been shown in guinea pigs, there are biological differences (even 10 fold) into how much vitamin C they required, Vitamin E helps recycle vitamin C and vice versa, Its an antioxidant, but is also important for maintaining cell integrity its located inside the cell membrane and prevents normal oxidative processes from happening there, Folate plays an important role in making new DNA, There are enzymes that are required to prevent and repair DNA damage, and then there are enzymes that require a micronutrient to prevent short term disease, If theres only so much of a micronutrient around, it will be used for the latter. Its really awful. Theres been some studies showing that high-dose melatonin in the 10 mg range, Im taking 9 mg per night and I totally stopped having them for the most part. Exercise is awesome of TONS of reasons, just do it!!! I did a sleep study once because I have sleep apnea.if(typeof ez_ad_units != 'undefined'){ez_ad_units.push([[250,250],'sleepline_com-large-mobile-banner-2','ezslot_9',663,'0','0'])};__ez_fad_position('div-gpt-ad-sleepline_com-large-mobile-banner-2-0'); Rogan: No I have a mouthpiece. OTdkZmZhMGY5NDk0YTA1MDhjZDMyOWJhZTA1MzI3YTI2ZTVmNzYyYTYwM2Ez It calculates heart rate, body movement, and temperature. A protective mechanism against viral, bacterial infections, Be careful of oxidized fish oil (this happens if its too old), Rhonda stopped taking it while breast feeding, she was taking 250 mg/day previously. NTNkNWIzNzc5MWUwMjI1NjY2NTQwZGM1NDk0ZjE4NjNjNmY5ZTk2ZDdiMDFk Made of 3 amino acids: glutatemic acid, glycine and cysteine, Our body bonds them by using an enzyme called, Other enzymes use glutathione as an antioxidant, With age we decrease the amount of glutathione we make, Because its made in our cells, there is no way to transport those three things into our cells by taking it orally pointless UNLESS Liposomal, Can bypass transport rules and get into cells, Not many studies, some animals have shown some get into the brain, but at a dose wayyyy higher than you can take/afford, Usually available at 100-400mg/dose and very expensive, You may get some in your brain, but not sure how much you get, Only tries to solve half the problem as the enzymes that use glutathione also decrease with age, so just getting more glutathione in your body, doesnt mean you can use it, 2014 study on TBI with mice and found that if they directly added glutathione to a mouse brain within 3 hours, they prevented like 70% of the damage (not human study), Ongoing studies to see what can be done with humans, Rapidly metabolized which activates a pathway in a liver to metabolize asap so not very usable, There would be a concern that this could impact the half-life of other medications/supplements you are taking be cautious, Still unclear at what dose and if could work at all in humans (trials ongoing ), Can get DHA into your brain via use a transporter called lisophotatital choline, Fish oil concentrates higher levels of DHA, but your brain doesnt need that much of DHA, but when it does it likes the Krill oil, Brain does need lots of EPA which Fish Oil does have, Obese/Diabetes are constantly in this state, Instead of vitamins, this combined with fiber/other things, Giving these to obese people with no other changes in the diet vs. lean people, Takes many weeks to start showing up in obese patients as they first need to fix some things, Recent study has shown that THC can reduce the accumulation of amyloid beta (move up), Patients at hospital after TBI (moderate to severe) with highest levels of THC were least likely to die (dose dependent effect), In mice: given low THC dose 48-hours before TBI or 1-7 days after, 2 types of Cannabinoids receptors in the brain, CB1 andCB2, Recent study showed agonizing CB1 lead to long term potentiation, Learning something new enhances a neuronal signal help learn long term, CB1 gets ride of the inhibitory, unless antagonized by amyloid beta, May be some acute effect on short term memory and might be a tradeoff benefit for long term potentiation, Cannabinoids in CB2 prevent the immune cells from activates and creating neuro-inflammation, More research now as $$$$ is involved in Colorado, etc. NWMyNjEwMGMwYmY4NGE0Y2FkNmY4NTJlYzljZDI5YWM5MTQ0ZGU5ZmU2ZWYy Its a mouthpiece that has a tongue depressor. Company About Jobs For the Record Communities For Artists Developers Advertising Investors Vendors Useful links Support Free Mobile App Cloudflare Ray ID: 7c0d628ddbd81541 Dr. Rhonda Patrick (@foundmyfitness) has a Ph.D. in biomedical science and is an expert on nutritional health. Dr. Patrick has been a guest of Joe Rogan Experience ten times. Just like people have adverse reactions to certain foods, Once study had a group do 24 high intensity interval cycling classes within 8 weeks at the end of the 8 weeks, average VO2 max was improved 12%, Rhonda recalls one study in which people got more benefits (pshycological and health) from walking within nature compared to on a treadmill, A womans VO2 max has been shown to increase after pregnancy, due to carrying around the extra weight, People with one allele of the ApoE4 gene, can have a 10-20x fold increased risk for CTE (Chronic Traumatic Encephalopathy)resulting from TBI (Traumatic Brain Injury), Rhonda has this gene, you can test for it with, Almost everything has sugar in it, if you go into a grocery store and pick up a random item, more likely that not there will be sugar in it, Saturated fat increases large LDL particle number, which isnt that bad, but when eaten in combination with refined sugar, some of these large LDL particles can be converted to small LDL particles, You cant gage someones risk for heart disease just by looking at LDL cholesterol number, you have to look at LDL size too, The PPAR-Alpha Gene and the Ketogenic Diet, So the ketogenic diet may in fact be detrimental to someone who doesnt have this, a high fat diet would lead to more free fatty acids in the blood stream, making someone more insulin insensitive, inflammatory biomarkers would also increase, Rhonda doesnt follow a ketogenic diet due to the fact that she really likes to get a lot prebiotic fiber for the microbiome, its hard to do this on a ketogenic diet, although its doable, We still really dont know how the ketogenic diet effects the microbiome (my gut biome diversity has gone down on a ketogenic diet), Bacteria in the microbiome eat the fermentable fiber we dont digest (from plants, seeds, nuts, legumes), Rhonda has concern that people dont get enough fermentable fiber on a ketogenic diet, Similar to ATP, used as an energetic currency throughout the body, used for etabolism, Improves physical performance, cognitive performance, Kevin Rose also talked about this supplement, in, Rhonda bought the supplement but isnt currently taking it, One study came out showing higher protein consumption from meat was associated with a higher all cause and cancer mortality. Thats how I felt. NDc0ODM1MDcwYmFmZWUwNTk3ZTcyZjgyZWNmMDliYmMzOGZhZmUwMzFjMDIz Joe Rogan and Rhonda Patrick cover a wide range of topics from pros and cons of ketosis, sauna use, the value of omega-3s, COVID, and much more. ZWFkNTE2OGE4Njk5Njk0N2EwZDNmZDYyMjlkMmI5NDU5YjYyMTRjOGIzYWE5 Dr. Rhonda Patrick appeared on episode #1474 of the Joe Rogan Experience to discuss a variety of topics including COVID-19, saunas, nutrition, and sleep. Ive gone places where I forgot it [the mouthpiece] and Im like fuck, Im going to sleep terrible. MDgzZTVjMTY0MzcxN2JmNDRhOGQ2ZTQyYzNjNmJlNmYxNzFjMjkyNGQ2YTMy Its totally calculating me as asleep. Is there a difference between infrared and standard? hundreds of millions of tax dollars More states will follow the money. It appears to me that Dr. Patrick might not be a true physiology nerd, and I am looking for counter arguments. "But if you're saying to yourself, 'Even if I get infected, I could do damage to somebody else, even if I have no symptoms at all' that's the reason why you've got to be careful and get vaccinated. ZjI5MDBkZTkyY2MyMjE2MDMzYmFlYmRlZTEzNzRmNzQ5YWU5OGM4ZTViZGZl OThmMzI0ZjQ5NzAxN2YwMGM5ZWQwOWQ0OWZmYmIxMmQzZDUzYjlmNjdlODU0 If you believe Wordfence should be allowing you access to this site, please let them know using the steps below so they can investigate why this is happening. Totally. Bonobos are also the least violent type of Ape, maybe because they have the most sex? On her last Joe Rogan Experience podcast, Rhonda mentioned she consumes 6 capsules of n-pure DHA now. #1474 - Dr. Rhonda Patrick The Joe Rogan Experience 1,043 views 14 May 2020 Transcribe your podcast [00:00:00] Hello, friends, welcome to the show. I somehow crawled from our bedroom out to the living room and by the time I woke up I had bruised myself I was like how did I get out here? This was the worst thats ever happened to me. The Private Medical team is joined by Dr. Josh Woolley to discuss the latest research on how psilocybin and related compounds impact the FREE when you join over 50,000 subscribers to the Podcast Notes newsletter. When the obese men underwent bariatric surgery (this reduces the size of the stomach to facilitate weight loss), the sperm DNA collected a year later, looked like that of the lean people. YjBmOTYzZmEyYjhlYzI4MDFlODZjZDA2ODNkMWI2ZDk0OTI2OTE4ZDBkZjQx YmYxYzAzNmY0YmM4NDQ4ZTdhYmZmYWIzMmI5ZWQ4YzAzMTE5ZTVkNTY0MDNj NjNmN2E4NDRhZmUyMjY2NzhjNTQ2NWJlYTllOTk4ZTM0ZWFmYzk4MDg0YWU4 Hearst Magazine Media, Inc. All Rights Reserved. Its associated with so many things. Her podcasts and other videos can be found at FoundMyFitness.comFull Episode: https://www.youtube.com/watch?v=uxM_CLsvieE\u0026index=203\u0026list=PLk1Sqn_f33KuU_aJDvMPPAy_SoxXTt_ub\u0026t=0s NDgxNWQxNTIwMDE3MTVlYjU4MDY4OTMwZTg2MDk3ZjRjNjFiMDIyNzVjNWU1 There is an issue between Cloudflare's cache and your origin web server. YzJkYmQxYzdmMzk3ZjI0ZmNiNDY5YjI5MWZkNWY2NWYyMjA4ZjQ5MGQxNDkx Its uncomfortable, youre wearing a mask over your face. I go listen I have it to. ), and cancer cells cant do this, Therefore, healthy cells are more resilient to the cancer treatment, Once Rhonda has stopped breast feeding her son, she plans to start regularly doing some long term fasts (2 days minimum), The gene that is important in determining whether you will experience placebo vs. nocebo, also controls the degradation of, People with less dopamine, are more likely to experience the nocebo response, Some schizophrenics are prescribed a very high dose (3-6 grams a day) of fish oil because their dopamine is lower in the prefrontal cortex, which is associated with he negative symptoms of schizophrenia, Rhonda takes capsulized fish oil from a friend who makes it in Norway she takes 5-6 grams a day (6 pills for her), Joe is favorable of it, but he eats too much meat (elk) to stay in ketosis, The same thing with being in ketosis, youll have BHB molecules in your blood, Short answer we dont know how similar BHB is to butyrate, so its tough to say, Perhaps the glucose in her brain is being spared for other things besides worrying, Joe suggests the perfect pre podcast meal the, Shell often take it before doing a podcast, or a big talk, It lowers her blood sugar levels pretty dramatically, so once the ketones ware off (after a couple of hours) she crashes, since she doesnt follow a ketogenic diet regularly, If she was already in ketosis, this wouldnt happen, Perhaps the crash could also be mitigated by consuming the HVMN with a higher carb meal, Brussel sprouts also contain sulforaphane, You cant cook the sprouts the enzyme that converts the precursor into active sulforaphane is heat sensitive, The mustard powder has the active enzyme that converts the precursor in the sprouts/kale into sulforophane, Rhonda has been taking 3 pills/day, each pill is 10mg with food, You get 2 copies of every gene 1 from mom, 1 from dad, The gene also increases the chances of a poor outcome if you have any kind of traumatic brain injury (TBI), If you have ApoE4. ", .css-13y9o4w{display:block;font-family:GraphikBold,GraphikBold-fallback,Helvetica,Arial,Sans-serif;font-weight:bold;margin-bottom:0;margin-top:0;-webkit-text-decoration:none;text-decoration:none;}@media (any-hover: hover){.css-13y9o4w:hover{color:link-hover;}}@media(max-width: 48rem){.css-13y9o4w{font-size:1.05rem;line-height:1.2;margin-bottom:0.25rem;}}@media(min-width: 40.625rem){.css-13y9o4w{font-size:1.28598rem;line-height:1.2;}}@media(min-width: 48rem){.css-13y9o4w{font-size:1.39461rem;line-height:1.2;margin-bottom:0.5rem;}}@media(min-width: 64rem){.css-13y9o4w{font-size:1.23488rem;line-height:1.3;}}12 Essential Multivitamins for Men, The Difference Between a Heart Attack and a Stroke, 9 Signs You May Develop Erectile Dysfunction, 6 Harmless Reasons You Can't Get An Erection, Signs You're Having an Existential Crisis, Covid Shots After the Public Health Emergency Ends, A Day in the Life of a (Clueless) Medical Intern, What the Covid Public Health Emergency End Means, What Is a Pulmonary Embolism From 'Succession'. When your neck muscles get big if you have a big tongue, and I have a big tongue when I lay down it closes the airway so my tongue slides back. Ive done it before where I come in and I cant form sentences. Click to reveal Buy: Pixel Eyewear Designer Computer Glasses, $75 from Amazon. The most recent guest on the hugely popular The Joe Rogan Experience is Rhonda Patrick PhD, a cell biologist whose work focuses on promoting a healthier, longer lifespan. Podcast Notes is a Signal From the Noise LLC Production, All Right Reserved, Berkshire Hathaway Annual Shareholders Meeting, Christopher Lockhead's Follow Your Different, Everyday Espionage Podcast with Andrew Bustamante, Feel Better, Live More With Dr. Rangan Chatterjee, Logocentrifugal Podcast With Chance Lunceford, Moonshots and Mindsets with Peter Diamandis, Network State Podcast with Balaji Srinivasan, Spearhead with Naval Ravikant and Babak Nivi, The Jolly Swagman Podcast with Joseph Walker, The Underworld Podcast with Danny Gold and Sean Williams, The Unraveling Podcast with Jocko Willink and Darryl Cooper, This Week in Startups with Jason Calacanis, Where It Happens with Sahil Bloom and Greg Isenberg, Most people on ketogenic diet are probably not actually achieving ketosis, Ketogenic diet isnt just about extreme low carb you have to be intentional about consuming very high fat, There are differences between fasting state and ketosis but you will make beta hydroxybutyrate and produce a lot of gabba in both cases which can improve cognitive function, Omega-3s are critical in diet: people with low omega-3 index have higher all cause mortality and lower lifespan, The quality of food makes a huge difference in micronutrient profile (and taste), Exercise can be tricky when trying to achieve ketosis: aerobic exercise can stimulate it, strength training can kick you out, Sauna use could offer a great way for the body to mimic exercise in people who are disabled, depressed, or otherwise not willing to exercise. At times we are compensated for the links you click at no cost to you. Particularly if their bills are piling up and they have no income. Download Audio. If I have a particularly intellectually challenging podcast Ill skip leg days. Dr. Rhonda Patrick makes her seventh appearance on the Joe Rogan Experience. As you get older your immune system declines List of JRE Rhonda Patrick Episodes. Patrick: If you dont wear it do you snore? Preview of Spotify. Healthy cells increase their stress response pathways when youre fasting (more heat shock proteins, more antioxidants etc. N2E3YTk1NThkMTRmY2VmMzc2Y2JiOWNkZGZhM2I1NzZjNTdmMTFkZTAwM2Mz Joe Rogan Experience Podcast Episode #1701 Dr. Rhonda Patrick ( @foundmyfitness ) has a PhD in biomedical science and is an expert on nutritional health, the brain and aging. Generated by Wordfence at Tue, 2 May 2023 4:05:36 GMT.Your computer's time: document.write(new Date().toUTCString());. Additionally, Dr. Rhonda graduated with a Bachelor of Science degree in biochemistry . Additional troubleshooting resources. Patrick: Its probably hard to sleep in those. Because you have to measure brain waves. Patrick: I use melatonin. "How do you know that the person who had myocarditis wouldn't have had it worse with Covid-19? Podcast Notes is a Signal From the Noise LLC Production, All Right Reserved, Berkshire Hathaway Annual Shareholders Meeting, Christopher Lockhead's Follow Your Different, Everyday Espionage Podcast with Andrew Bustamante, Feel Better, Live More With Dr. Rangan Chatterjee, Logocentrifugal Podcast With Chance Lunceford, Moonshots and Mindsets with Peter Diamandis, Network State Podcast with Balaji Srinivasan, Spearhead with Naval Ravikant and Babak Nivi, The Jolly Swagman Podcast with Joseph Walker, The Underworld Podcast with Danny Gold and Sean Williams, The Unraveling Podcast with Jocko Willink and Darryl Cooper, This Week in Startups with Jason Calacanis, Where It Happens with Sahil Bloom and Greg Isenberg, Sauna: if you have access use the sauna regularly to improve cardiovascular health and immune functions take a hot bath if you dont have access, Theres a big difference between oral vitamin C and Intravenous vitamin C, You can take vitamin C orally but will need a big dose and it still wont have the same effect; IV once per week if you can, Sleep plays a crucial role in immunity, homeostasis, and regulation of body functions, People are actively working on monoclonal antibodies, Improved therapeutic treatments coming, including more repurposing of drugs that will make things less scary, As you get older your immune system declines, There are lifestyle components of immune system you can be proactive about: exercise, sleep, supplements, nutrition, gut-microbiome health, Besides age, the major regulator of immune function seems to be previous virus exposure, not genetics, At any given point you have antibodies against 10 different viruses but youre not always getting sick, 50-80% of US population has had CMV and most people dont ever know they have had it and show no symptoms, CMV impacts immune function differently depending on when you get it, When youre young, it enhances immune response but for older people its deleterious, Interesting tie-in to COVID-19 because we know older people are more prone to severity, Its likely that theres some cross-immunity happening since SARS-COV-2 viruses is part of beta coronaviruses along with SARS-CoV-1 and MRSA, 15-30% of common colds come from coronaviruses so theres a good hypothesis that potentially one or two of common cold virus antibodies could interact with SARS-CoV-2 and neutralize it, Antibody binds to virus and instead of neutralizing it, changes the configuration so the virus can get into the cell better, This activates the immune system and causes pathology, This results in a higher viral load without antibodies to neutralize, Weve seen it happen with coronaviruses, including SARS-CoV-1 and MRSA, The spike region is where antibodies bind and is also the region the virus uses to get into the cell, Currently seeing two major strain mutations in the spike regions one mutation more prominent in Asia, one mutation more predominant in Europe and North America, Brings to light an interesting genetic link to mutations, Theres a theory that the mutation is causing peoples immune system to become more active and lead to severe COVID-19, Monoclonal antibodies: identify specific antibody that binds to spike protein and manufacture them, Problem is this will offer short lived protection since you are not making your own antibodies as you would with a vaccine, Continuous exploration into repurposing drugs and combination drug treatments, Anecdotally, the majority of people on ventilators die partly because ventilators cause more damage to the lungs and can induce more damage, But its hard to say which came first did the ventilator do the damage or was the damage so severe that the patient needed a ventilator, People with Type O blood seem to be less susceptible to contracting COVID-19, People with Type O blood create Type A antibodies which bind to spike region and neutralize antibody so it cant enter the cell, We saw this in SARS-CoV-1 so maybe same for SARS-CoV-2, Another (unproven) theory: Type O blood people have lower levels of blood factor involved in clotting, Hearing more stories that some prisoners are trying to contract SARS-CoV-2 to get out of jail by spitting in a cup and passing to others, First off, its important to distinguish between asymptomatic and pre-symptomatic, Some people do not have symptoms at the time of testing but develop symptoms later so are actually pre-symptomatic, Its possible that viruses have already gone around that environment so antibodies from those viruses are helping in immunity from SARS-CoV-2, Rhonda was also searching to literature to see whether inmates are vaccinated prior to entering but couldnt find that information, Poor sleep has a huge impact on glucose and spikes and also plays a role in maintaining optimal immune functions, Rhonda takes melatonin to help her sleep, 10 mg/day, Regulating circadian rhythm is crucial for sleep, Rhonda makes sure to have bright light exposure in the morning (e.g., opening curtains, walking outside), and changes the lighting in the house in the evening to red lights, 70% of US population has insufficient Vitamin D levels; 28% are deficient, Body can generate naturally when exposed to sun daily, Obese people in US are also more likely to be vitamin D deficient, Genetic polymorphisms: people that have variations in genes that cause them to have less vitamin D, These people are more likely to die from respiratory infection, African Americans in the US are 28x more deficient in vitamin D than Caucasians, A recent study that looked at COVID-19 patients observed an inverse relationship between vitamin D levels and COVID-19 symptoms: the lower the vitamin D levels, the higher the severity of COVID-19, In Indonesia almost all patients that died from COVID-19 were vitamin D deficient, Melanin blocks ability to produce Vitamin D, In the US and Europe, African Americans and black people are more likely to die from COVID-19, Even when adjusting for SES and lifestyle factors, this was still true so something else must be happening, Tolerable upper intake is 4000 IUs per day but its best to get vitamin D blood test to measure levels, There are clinical studies exploring the role of vitamin D but not many in the US, Rhonda wants to see nurses and first responders take vitamin D to see the role in prevention but those studies are not being done, Joe uses the sauna 7 days/week, 180-degrees for 25 min, Rhonda uses the sauna 5 days/week, 180-degrees for 25 min, Heart rate variability improves, blood pressure goes down, cardiovascular health improves, all-cause mortality decreases, Sauna use also improves immune system and makes you more resilient against infection, Brain-derived neurotropic factors (BDNF) increases with exercise and heat stress (sauna), The positive benefits of physical activity on the cardiovascular system were enhanced when sauna was added, Sauna use increases heat shock proteins which prevent muscle atrophy, neurodegenerative genes, and have anti-depressant effects, People who sat in 160-degree sauna for 30 minutes had a 60% increase in heat shock protein compared to baseline, Large Harvard study being done to assess whether hot yoga increases heat shock protein, Heat shock protein have antiviral activity against influenza A, Regular sauna is heating ambient air which in turn raises core body temperature, Infrared saunas are directly heating body without heating the ambient air for example, in a heating tent or blanket, We know more about the effects of dry sauna, For people who dont have access to sauna, a hot bath is a good modality for heat shock protein, Studies being done to assess whether sauna can have anti-depressant effect on depressed patients, Saunas could also provide an avenue for giving sedentary and disabled people the benefits of physical activity without exercising, Ice baths and cold showers can be comparable to cryotherapy but you have to stay in the cold water longer, Cold shock protein hasnt really been measured in humans, instead whats measured is norepinephrine which has been shown to increase, Cold shock protein and hot shock protein have been shown to improve mood as well, The pharmacokinetics of vitamin C are very different in oral vs IV consumption, Oral vitamin C is good for immune function, etc.
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